Fish composition in a complex freshwater estuary: Environmental DNA metabarcoding versus capture surveys

Published Article

United States

Publication date: September 1, 2025

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A comparison of eDNA metabarcoding and multigear capture surveys in the St. Louis River estuary shows that eDNA detects more species and at higher frequencies, including unexpected taxa with no prior basin records. However, eDNA signals were spatially homogenized and often mismatched with capture‑based distributions, indicating limited ability to resolve fine‑scale patterns in a complex estuary. The study concludes that eDNA is powerful for system‑wide species detection, while capture surveys remain essential for spatially explicit fisheries and habitat management.

Subject Tags

  • Wildlife
  • Conservation Technology
  • Estuary

Abstract

Objective

The potential for environmental DNA (eDNA) to disperse widely from source organisms enables high detection efficiency but raises questions about eDNA's ability to differentiate fine-scale spatial patterns relative to conventional fish capture data.

Methods

We evaluate these questions in the St. Louis River estuary—a hydrologically and spatially complex coastal system within Lake Superior that supports a diverse assemblage of resident and migratory fish species—via comparison of eDNA metabarcoding (12S and 16S loci) to multigear capture survey data from 2 years and two seasons.

Results

The eDNA and capture surveys collectively yielded 68 fish species: 2 species detected only by capture, 27 detected only by eDNA, and 39 shared across both survey types but having generally higher occurrence frequencies with eDNA than capture. Six species detected only by eDNA were unexpected, having no prior records in the Lake Superior basin. Data from paired eDNA and capture stations showed little relationship between the two survey types, with capture yielding species at stations that eDNA did not, eDNA detecting species in different habitats and distant locations from any captures, and assemblage patterns homogenized in eDNA surveys relative to capture surveys.

Conclusions

Our study finds that eDNA is a sensitive tool for assessing species presence at the system scale but that capture surveys may better yield the fine-scale spatial distribution information of interest to fisheries and habitat managers, especially in spatially and hydrologically complex systems.

Citation

Trebitz, A. S., Hoffman, J. C., Peterson, G. S., Hatzenbuhler, C., Pilgrim, E., Okum, S., ... & Myers, J. T. (2025). Fish composition in a complex freshwater estuary: Environmental DNA metabarcoding versus capture surveys. Transactions of the American Fisheries Society, 154(6), 657-674. https://doi.org/10.1093/tafafs/vnaf036

TNC Authors

  • Lindsay Chadderton
    Program Director, AIS, Wisconsin
    The Nature Conservancy
    Email: lchadderton@tnc.org

  • Andrew Tucker
    Conservation Scientist, Wisconsin
    The Nature Conservancy
    Email: atucker@tnc.org